We observed the field of GRB 100305A (Troja et al., GCN 10470) with the 0.6m Super-LOTIS telescope located at Kitt Peak National Observatory beginning 106 seconds after the trigger. Observations were carried out in the R band for approximately 45 minutes under good conditions. We do not detect any sources within the XRT enhanced error circle (Osborne et al., GCN 10474) or the source detected by Gemini-N (Cucchiara, GCN 10473). Band Exptime co-adds time UL ------------------------------------- R 10 5 106 > 17.5 R 20 5 202 > 19.2 R 60 30 389 > 20.5 Exptime is given in seconds; time is seconds after trigger of first observation. All limits given relative to USNO B1.0 field stars.